Searchable abstracts of presentations at key conferences in endocrinology

ea0070ep543 | Hot topics (including COVID-19) | ECE2020

Are women with osteoporosis treated with denosumab at risk of severe COVID-19?

Maria Formenti Anna , Pedone Erika , Di Filippo Luigi , Massimo Ulivieri Fabio , Giustina Andrea

Coronavirus disease 2019 (COVID-19), is a primarily respiratory infection which can lead to severe syndrome needing hospitalization and assisted ventilation with high lethality. In a recent meta-analysis of 33 RCTs increased risk of severe infections on treatment with Denosumab, widely used for treatment of osteoporosis, was found specifically for ear, nose, and throat. In fact, by inhibiting the receptor activator of nuclear factor κ-Β ligand, denosumab acts as an i...